abstract：:Electronic compensation to overcome thermal artifacts during plethysmographic estimations of airway resistance is now used routinely in adults and school-age children, and was shown to be a valuable means of discriminating airway function between preschool children with and without lung disease. A similar system is no...

journal_title：Pediatric pulmonology

authors： Subbarao P,Hulskamp G,Stocks J

更新日期：2005-07-01 00:00:00

abstract：:IL-10 is an anti-inflammatory cytokine that may have a protective role in acute lung injury. IL-10 expression is affected by a single-nucleotide polymorphism (SNP) located at position -1082 (G to A). The A allele is associated with lower IL-10 production. Low IL-10 production has been linked to the development of BPD....

journal_title：Pediatric pulmonology

authors： Yanamandra K,Boggs P,Loggins J,Baier RJ

更新日期：2005-05-01 00:00:00

abstract：:The jet nebulizer is a common device used for administering aerosol medication in young children. However, compared to a metered dose inhaler-spacer (MDI-spacer), it takes more time and personnel. This study aimed to compare the efficacy of salbutamol aerosol therapy given via these two devices in young wheezing child...

journal_title：Pediatric pulmonology

authors： Deerojanawong J,Manuyakorn W,Prapphal N,Harnruthakorn C,Sritippayawan S,Samransamruajkit R

更新日期：2005-05-01 00:00:00

abstract：:Spirometry is used to monitor respiratory progress in children with Duchenne muscular dystrophy (DMD). Mucociliary clearance depends on cough strength, which can be measured by peak cough flow (PCF). It is not routinely measured in most centers. When the PCF falls below 270 l/min, mucociliary clearance is likely to be...

journal_title：Pediatric pulmonology

authors： Gauld LM,Boynton A

更新日期：2005-05-01 00:00:00

abstract：:Pseudomonas aeruginosa is often cultured from the airways of children with tracheostomies. P. aeruginosa produces exotoxin A (ETA) and type III cytotoxins. This study tested the hypothesis that children with tracheostomies are colonized by P. aeruginosa that express these virulence factors and will have antibodies dir...

journal_title：Pediatric pulmonology

authors： Rao AR,Splaingard MS,Gershan WM,Havens PL,Thill A,Barbieri JT

更新日期：2005-05-01 00:00:00

abstract：:Exercise-induced asthma (EIA) is a possible cause of poor physical performance in children. No data are available on the value of respiratory symptoms to discriminate children with bad physical fitness from children with EIA. We evaluated respiratory symptoms in school-age children during and after exercise in relatio...

journal_title：Pediatric pulmonology

authors： De Baets F,Bodart E,Dramaix-Wilmet M,Van Daele S,de Bilderling G,Masset S,Vermeire P,Michel O

更新日期：2005-04-01 00:00:00

abstract：:Pneumocyte apoptosis is implicated in the pathophysiology of acute inflammatory lung injuries in newborns and adults. Pulmonary angiotensin (ANG) II contributes to lung epithelial apoptosis in vitro, but its role in acute lung injury in vivo is unclear. We therefore studied the effects of ANG II receptor action on the...

journal_title：Pediatric pulmonology

authors： Lukkarinen HP,Laine J,Aho H,Zagariya A,Vidyasagar D,Kääpä PO

更新日期：2005-04-01 00:00:00

abstract：:Our objective was to study meconium-induced lung injury in isolated perfused rat lungs exposed to anoxia. Our working hypothesis was that meconium-induced lung injury is independent of preexisting hypoxia, and that hypoxia will increase severity of lung injury observed after meconium aspiration. We compared five diffe...

journal_title：Pediatric pulmonology

authors： Wisniewski WM,Zagariya AM,Pavuluri N,Srinivasan H,Shankarao S,Vidyasagar D

更新日期：2005-04-01 00:00:00

abstract：:New Zealand children's morbidity from respiratory disease is high. This study examines whether subclinical ciliary abnormalities underlie the increased prevalence of respiratory disease in indigenous New Zealand children. A prospective study enrolled a group of healthy children who were screened for respiratory diseas...

journal_title：Pediatric pulmonology

authors： Edwards EA,Douglas C,Broome S,Kolbe J,Jensen CG,Dewar A,Bush A,Byrnes CA

更新日期：2005-03-01 00:00:00

abstract：:Neutrophil elastase is present at high levels in airway fluid of patients with cystic fibrosis (CF), and is responsible for considerable inflammatory damage. Human monocyte/neutrophil elastase inhibitor (MNEI), a 42-kDa serpin protein, is an effective inhibitor of neutrophil elastase, cathepsin G, and proteinase-3, re...

journal_title：Pediatric pulmonology

authors： Woods DE,Cantin A,Cooley J,Kenney DM,Remold-O'Donnell E

更新日期：2005-02-01 00:00:00

abstract：:Foreign-body aspiration (FBA) is a commonly encountered serious problem during childhood, accounting for 7% of lethal accidents in children aged 1-3 years. Bronchoscopy is indicated when a clear history of FBA is present, but the history may be unreliable. Clinical manifestations can be seen in various diseases, and w...

journal_title：Pediatric pulmonology

authors： Aslan AT,Yalcin E,Ozcelik U,Ciftci AO,Kiper N

更新日期：2005-02-01 00:00:00

abstract：:Environmental tobacco smoke, also called passive smoking, was shown to have adverse effects on the health of children. Hydrogen peroxide (H2O2) is proposed as a sensitive marker of oxidative injury and inflammatory processes in the airways, being increased in adult active cigarette smokers. We tested whether passive s...

journal_title：Pediatric pulmonology

authors： Doniec Z,Nowak D,Tomalak W,Pisiewicz K,Kurzawa R

更新日期：2005-01-01 00:00:00

abstract：:Physicians and physiotherapists who care for CF patients have recommended the use of trampolines as a physiotherapeutic tool for enhancing cardiopulmonary performance, encouraging sputum production, and improving general well-being. Despite some therapeutic and recreational benefits associated with trampoline use, pap...

journal_title：Pediatric pulmonology

authors： Barak A,Wexler ID,Efrati O,Bentur L,Augarten A,Mussaffi H,Avital A,Rivlin J,Aviram M,Yahav Y,Kerem E

更新日期：2005-01-01 00:00:00

abstract：:We evaluated 4 patients who developed severe, symptomatic stridor during maximal cardiopulmonary exercise testing, all referred due to exercise-related dyspnea. All underwent resting, unsedated transnasal fiberoptic laryngoscopy and had normal findings. Four patients performed repeat maximal exercise testing with fibe...

journal_title：Pediatric pulmonology

authors： Fahey JT,Bryant NJ,Karas D,Goldberg B,Destefano R,Gracco LC

更新日期：2005-01-01 00:00:00

abstract：:We report on a 7-month old infant with severe respiratory distress secondary to a paratracheal bronchogenic cyst. Respiratory relief was achieved by transtracheal puncture of the cyst. Surgical removal of the cyst was performed 1 week later because of radiological evidence of reaccumulation of fluid. ...

journal_title：Pediatric pulmonology

authors： De Baets F,Van Daele S,Schelstraete P,Haerynck F,Vermassen F,Broers C

更新日期：2004-12-01 00:00:00

abstract：:Systemic onset juvenile rheumatoid arthritis is the most common rheumatologic disorder of childhood. Pleuropulmonary manifestations are rare in children in this multiorgan disease, and are usually not severe. The diagnosis of systemic onset juvenile rheumatoid arthritis is made by exclusion, in the presence of clinica...

journal_title：Pediatric pulmonology

authors： Rochat I,Sayegh Y,Gervaix A,Rimensberger PC,Argiroffo CB

更新日期：2004-12-01 00:00:00

abstract：:Nitric oxide (NO) that is produced within the airways can be measured in the exhaled air. Concentrations of exhaled NO (FENO) are decreased in cystic fibrosis (CF) and, in cross sectional studies, have been shown to be even lower in patients with more advanced pulmonary disease. This may result from retention and meta...

journal_title：Pediatric pulmonology

authors： Grasemann H,Lax H,Treseler JW,Colin AA

更新日期：2004-11-01 00:00:00

abstract：:Lower respiratory tract infections (LRTI) are common in the first year of life and are mostly caused by viruses. Severity of LRTI in infants is associated with early-life environmental factors. Genetic association studies also suggest a role of heredity in susceptibility to acute bronchiolitis. We designed a case cont...

journal_title：Pediatric pulmonology

authors： Goetghebuer T,Kwiatkowski D,Thomson A,Hull J

更新日期：2004-10-01 00:00:00

abstract：:Phrenic nerve paralysis is a condition typically occurring after invasive procedures in the chest and neck. Here we describe a case of transient unilateral diaphragmatic paralysis in a child with status asthmaticus complicated by complete right lung atelectasis. Common causes of this disorder and possible implications...

journal_title：Pediatric pulmonology

authors： Santuz P,Piccoli A,Zaglia F,Biban P

更新日期：2004-09-01 00:00:00

abstract：:Our objective was to determine whether a simple method of maintaining positive pressure ventilation during nonbronchoscopic bronchoalveolar lavage (NB-BAL) would successfully reduce the incidence and/or severity of desaturation events. Our design was a clinical trial with historical controls. Seventy ventilated pediat...

journal_title：Pediatric pulmonology

authors： Morrow B,Futter M,Argent A

更新日期：2004-09-01 00:00:00

abstract：:Epidemiological data suggest that respiratory syncytial virus (RSV) infection in early life is a risk factor for later asthma. There are no prospective studies on RSV infection starting from infancy progressing through childhood into adulthood. We followed up a cohort of children, hospitalized for RSV bronchiolitis or...

journal_title：Pediatric pulmonology

authors： Korppi M,Piippo-Savolainen E,Korhonen K,Remes S

更新日期：2004-08-01 00:00:00

abstract：:This paper assesses the effectiveness of aerosolized tobramycin (TOBI) on cystic fibrosis (CF) lung disease, using a radiologic tool. The published tool, the age-based severity curve (ABS), is derived from Brasfield scoring of chest X-rays (CXR). This study evaluates both the usefulness of the ABS as an assessment too...

journal_title：Pediatric pulmonology

authors： Slattery DM,Zurakowski D,Colin AA,Cleveland RH

更新日期：2004-07-01 00:00:00

abstract：:The goal of the present investigation was to describe the prevalence of and clinical factors associated with sleep-disordered breathing in children and adolescents. Children and adolescents (3,680 in all, 1-18 years old) attending schools in central Greece were surveyed by questionnaires distributed to parents. We fou...

journal_title：Pediatric pulmonology

authors： Kaditis AG,Finder J,Alexopoulos EI,Starantzis K,Tanou K,Gampeta S,Agorogiannis E,Christodoulou S,Pantazidou A,Gourgoulianis K,Molyvdas PA

更新日期：2004-06-01 00:00:00

abstract：:We conducted a survey to determine parent-reported asthma prevalence, morbidity, and healthcare utilization among 3527 children attending public schools (n = 2849) and private schools (n = 678) in San Juan, Puerto Rico. Schools were randomly selected from each of 12 geographic regions of the San Juan metropolitan area...

journal_title：Pediatric pulmonology

authors： Nazario S,Casal JR,Torres-Palacios A,Rodriguez W,Delamater AM,Applegate EB,Piedimonte G,Wanner A

更新日期：2004-05-01 00:00:00

abstract：:Patients with cystic fibrosis (CF) can be discriminated from healthy subjects by measurement of the nasal potential difference, which has become a useful outcome measure for therapies directed toward correcting defective electrolyte transport in CF. A standard operating procedure was developed by a CF Foundation clini...

journal_title：Pediatric pulmonology

authors： Standaert TA,Boitano L,Emerson J,Milgram LJ,Konstan MW,Hunter J,Berclaz PY,Brass L,Zeitlin PL,Hammond K,Davies Z,Foy C,Noone PG,Knowles MR

更新日期：2004-05-01 00:00:00

abstract：:Obstructive sleep apnea syndrome (OSAS) has been associated with reduced neurocognitive performance in children, but the underlying etiology is unclear. The aim of this study was to evaluate the relationship between hypoxemia, respiratory arousals, and neurocognitive performance in snoring children referred for adenot...

journal_title：Pediatric pulmonology

authors： Kennedy JD,Blunden S,Hirte C,Parsons DW,Martin AJ,Crowe E,Williams D,Pamula Y,Lushington K

更新日期：2004-04-01 00:00:00

abstract：:Our objective was to review the clinical features and radiographic manifestations of chest wall lesions in a pediatric chest unit. Twenty-five patients (11 males and 14 females, aged 14 months to 15 years) were suspected of having a chest wall lesion on the basis of clinical examination and chest radiograph. A retrosp...

journal_title：Pediatric pulmonology

authors： Wong KS,Hung IJ,Wang CR,Lien R

更新日期：2004-03-01 00:00:00

abstract：:The quantity and composition of airway surface liquid (ASL) are essential to host defense. To date, attempts to harvest ASL and measure its composition have yielded conflicting results. We investigated the physical principles underlying two techniques that were proposed for harvesting ASL: filter paper pledgets and po...

journal_title：Pediatric pulmonology

authors： Landry JS,Landry C,Cowley EA,Govindaraju K,Eidelman DH

更新日期：2004-02-01 00:00:00

abstract：:Early detection of progressive lung disease in cystic fibrosis (CF) may lead to better treatment and prognosis. Routine lung function indices may be relatively insensitive markers of peripheral airway obstruction and alveolar collapse. We hypothesized that the single-breath diffusion capacity of the lung for carbon mo...

journal_title：Pediatric pulmonology

authors： Merkus PJ,Govaere ES,Hop WH,Stam H,Tiddens HA,de Jongste JC

更新日期：2004-01-01 00:00:00

abstract：:Our objective was to determine the repeatability of bronchial responsiveness to mannitol dry powder (MDP) as an objective marker of asthma in children. MDP challenge was performed in children with stable asthma at the same time of the day on two separate occasions within a week. The test was terminated after a 15% fal...

journal_title：Pediatric pulmonology

authors： Barben J,Roberts M,Chew N,Carlin JB,Robertson CF

更新日期：2003-12-01 00:00:00

abstract：:Malacoplakia is an unusual inflammatory condition with distinctive histologic features. Involvement of the lung is quite uncommon and is rarely described in paediatrics. We report on a case of pulmonary malacoplakia in a teenage girl. ...

journal_title：Pediatric pulmonology

authors： Kumar P,Rassl DM,Hamilton JR,Spencer DA

更新日期：2003-11-01 00:00:00

abstract：:The term "atypical" pneumonia has been used to differentiate infections caused by Chlamydia pneumoniae, Mycoplasma pneumoniae, Legionella, and other related organisms from pneumonia caused by classic bacteria, the prototype being Streptococcus pneumoniae. However, recent studies demonstrated that the clinical presenta...

journal_title：Pediatric pulmonology

authors： Hammerschlag MR

更新日期：2003-11-01 00:00:00

abstract：:The collection of sputum for microbiological examination in young cystic fibrosis patients can be very difficult. However, a knowledge of bacterial flora colonizing the patient's airways is of paramount importance for proper antimicrobial therapy. It is also known that cystic fibrosis patients colonized by Pseudomonas...

journal_title：Pediatric pulmonology

authors： Vogelberg C,Hirsch T,Rösen-Wolff A,Kerkmann ML,Leupold W

更新日期：2003-10-01 00:00:00

abstract：:The cotton rat was evaluated as a model for anti-inflammatory and antiviral influenza therapy. Beginning 3 days after intranasal infection with 10(7) tissue culture infectious doses-50% (TCID)(50) of an H3N2 human influenza, animals were treated topically via intranasal lavage with a range of doses of triamcinolone ac...

journal_title：Pediatric pulmonology

authors： Ottolini M,Blanco J,Porter D,Peterson L,Curtis S,Prince G

更新日期：2003-10-01 00:00:00

abstract：:Our objective was to compare the effectiveness of maximum forced expiratory flow measured at functional residual capacity (V'maxFRC) and the ratio of flow at 75% of the forced expiratory volume to peak forced expiratory flow (FEF(75)/FEF(peak)) for detecting bronchodilator-related changes in wheezy infants. In 55 infa...

journal_title：Pediatric pulmonology

authors： Sheikh S,Castile R,Hayes J,McCoy K,Eid N

更新日期：2003-09-01 00:00:00

abstract：:Our purpose was to identify and further characterize physiologic mechanisms relevant to autoresuscitation from hypoxic apnea in infants dying suddenly and unexpectedly. We studied cardiorespiratory recordings of 24 infants (age range, 0.8-21 months) who died suddenly while being monitored at home. These recordings wer...

journal_title：Pediatric pulmonology

authors： Sridhar R,Thach BT,Kelly DH,Henslee JA

更新日期：2003-08-01 00:00:00

abstract：:Pneumomediastinum is uncommon in pediatric medical practice, outside the neonatal period. While asthma or respiratory infections are the most frequent underlying causes, it is important not to forget the possibility of foreign body aspiration, particularly after the clinical presentation. ...

journal_title：Pediatric pulmonology

authors： Findlay CA,Morrissey S,Paton JY

更新日期：2003-07-01 00:00:00

abstract：:Few data are known about the effects of sleep-related breathing disorders (SRBD) on the cardiovascular system in adolescents. Forty healthy adolescents (mean age, 13.7 +/- 1.6 years) answered a questionnaire regarding symptoms of sleep-related breathing disorders (SRBD) and underwent a cardiorespiratory polygraphy and...

journal_title：Pediatric pulmonology

authors： Sánchez-Armengol A,Rodríguez-Puras MJ,Fuentes-Pradera MA,Quintana-Gallego E,Borja-Urbano G,Cayuela A,Capote F

更新日期：2003-07-01 00:00:00

abstract：:This report describes a patient with biliary atresia (BA) associated with polysplenia syndrome who showed a rapid progression of intrapulmonary arteriovenous shunting (IPS), resulting in a fatal outcome. Intrauterine ultrasonography at 36 weeks of gestation revealed fetal abnormalities, including situs inversus, absen...

journal_title：Pediatric pulmonology

authors： Kimura T,Hasegawa T,Sasaki T,Okada A,Mushiake S

更新日期：2003-06-01 00:00:00

abstract：:In past decades, several chest radiograph scoring systems for cystic fibrosis were developed. This study was performed to compare interobserver variability of six different radiograph scores and to correlate them with clinical parameters. Thirty chest radiographs of 30 patients with cystic fibrosis were scored accordi...

journal_title：Pediatric pulmonology

authors： Terheggen-Lagro S,Truijens N,van Poppel N,Gulmans V,van der Laag J,van der Ent C

更新日期：2003-06-01 00:00:00